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pentobarbital will lower the level or effect of ambrisentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.pentobarbital will lessen the level or effect of etonogestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will lessen the level or influence of mi